Endocrine Abstracts

Objective: Neurosteroids, a unique hormone group, are recognized for their impact on cognitive processes. The primary objective is to assess the correlation between cognitive function and NS levels in cases of Cushing’s disease and a control group of nonfunctional pituitary adenoma (NFPA).Design: The study comprised 26 individuals diagnosed with Cushing’s disease (CDG), while a control group (CG) consisted of 14 age-gender matched participants ...

Introductıon: Rathke’s cleft cysts (RCCs) are benign lesions originating from the epithelial remnants of Rathke’s pouch with a peak incidence at 30–50 years of age. It is detected at a rate of 13–33% in several autopsy series. RCC is usually asymptomatic and diagnosed incidentally. In symptomatic cases, common symptoms are headache, visual disturbance, and symptoms related to hypopituitarism.Case: A 28-year-old male patient prese...

Neurosteroids refer to hormones with a steroid structure and, their synthesis pathways are identical to those of traditional steroids. However, neurosteroids are generated denovo in the central and peripheral nervous systems and utilize cell surface receptors. Few animal studies indicated synthesis of NS in pituitary. Presence of neurosteroids in human pituitary adenomas(PAs) has yet to be assessed. This is preliminary data of an ongoing study. Seventyseven specimens from huma...

Background: Hypophysitis is a rare group of disease characterized with infla mmation of the pituitary gland. Rarity of the disease obviates development of a treatment strategy. We aimed to present the nationwide data of the demographics, clinical and radiological characteristics, treatment modalities and responses of the patients diagnosed with hypophysitis in a retrospective manner.Methods: The endocrinology clinics all over the country were invited to ...